Kernicterus Bilirubin Levels ppts

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Hyperbilirubinemia - Stanford University

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Hyperbilirubinemia - Stanford University

Objectives. Understand pathway where bilirubin comes from. Physiologic vs Pathologic Hyperbilirubinemia. Understand the risk for Kernicterus . Understand why we care ...

Date added: October 18, 2013 - Views: 12

Neonatal jaundice education presentation -...

Kernicterus is a pathology term, ... • Do not measure bilirubin levels routinely in babies who are not visibly jaundiced ... Neonatal jaundice education presentation

Date added: June 27, 2015 - Views: 4

PowerPoint Presentation

... Due to immaturity of the enzymes involved in bilirubin conjugation High levels of unconjugated bilirubin ... known as kernicterus If bilirubin levels ...

Date added: October 25, 2011 - Views: 186

Bilirubin - University of Massachusetts Lowell

Bilirubin. The yellow breakdown product of normal heme catabolism. The principle pigment in bile. Bilirubin circulates in the bloodstream in two forms:

Date added: December 3, 2014 - Views: 16

MLAB 2401: Clinical Chemistry Keri Brophy-Martinez

... Onset seen at bilirubin levels > 3.0 mg/dL Kernicterus Yellow staining of the meninges of the brain due to bilirubin Found in newborns Causes brain ...

Date added: May 18, 2013 - Views: 12

The Normal Newborn, Assessment, Care, Feeding

The Normal Newborn: Assessment, Care, ... Increased Bilirubin Levels Jaundice in the 1st ... Hepatic Function Increased Bilirubin Levels Kernicterus Neurologic ...

Date added: October 2, 2011 - Views: 528

Jaundice Noted in the First 24 Hours After Birth...

Overview Introduction Jaundice in newborns and kernicterus Infant ... permanent brain damage from very high bilirubin levels ... Jaundice Noted in the First 24 ...

Date added: September 12, 2011 - Views: 100

Obstructive Jaundice - Wikispaces

This hyperbilirubinemia subsequently causes increased levels of bilirubin in ... Obstructive Jaundice ... of bilirubin,a condition known as kernicterus ...

Date added: March 30, 2014 - Views: 26

Bilirubin Metabolism - Yola

Bilirubin Metabolism in the Liver. Uptake of Bilirubin by hepatocytes: Bilirubin dissociates from its carrier albumin & enters hepatocytes. Conjugation

Date added: August 11, 2014 - Views: 1

Blood Cells and Vessels - Dr Magrann

Red Blood Cell Breakdown. Hemoglobin in RBC’s is broken down to bilirubin. Bilirubin is excreted in bile and urine, and elevated levels may indicate certain diseases.

Date added: February 7, 2014 - Views: 29

Respiratory Therapy Licensure Alabama

Decreased clearance of bilirubin from the plasma due to decrease levels of ligandin and uridine ... Most serious complication is kernicterus (bilirubin pigment ...

Date added: August 16, 2013 - Views: 4

Slide 1

Background. Exchange transfusion is recommended for newborns with total serum bilirubin (TSB) levels thought to place them at risk for cerebral palsy (CP).

Date added: March 4, 2015 - Views: 1

Indication -

Kernicterus: * Bilirubin deposits typically in ... No evidence shows that this practice is of practical value in neonates with normal albumin levels. Side effects of ...

Date added: August 16, 2015 - Views: 1

Evidence-Based Medicine for AAP Leadership

First use of phototherapy History 1970s Bilirubin toxicity at lower levels? ... Kernicterus rare if Total Serum Bilirubin (TSB) kept < 20 mg/dl RCT: ...

Date added: November 6, 2011 - Views: 59

What is there to Know About a Yellow Baby?

We no longer see the high bilirubin levels that necessitate double volume exchange transfusion. History. Kernicterus. Why do we Worry? Unconjugated bilirubin ...

Date added: November 4, 2013 - Views: 16

PowerPoint Presentation

Kernicterus (bilirubin encephalopathy) can result from untreated hypergbilirubinemia with bilirubin levels at or higher than 20 mg/dl → mental retardation.

Date added: March 21, 2013 - Views: 133

Neonatal Anesthesia - Ain Shams University

Neonatal Anesthesia ... low serum protein levels are liable to get Kernicterus (bilirubin encephalopathy) due to increased levels of unconjugated serum bilirubin.

Date added: May 13, 2013 - Views: 35


NEURO-FOR-THE-NOT-SO-NEURO-MINDED ... Athetoid (slow, writhing movements) cerebral palsy—kernicterus (elevated bilirubin levels in newborns) ...

Date added: November 23, 2013 - Views: 48

Jaundice and Kernicterus in the Newborn - Fort...

Jaundice and Kernicterus in the Newborn B. Paul Choate, M.D. Fort Carson MEDDAC Introduction Neonatal jaundice affects 60% of term babies and 80% of pre-term babies ...

Date added: October 23, 2014 - Views: 18

Slide 1

Bilirubin is a Neurotoxin Who is ... But kernicterus, ... A small percentage of babies with jaundice have dangerously elevated levels of a naturally occurring ...

Date added: May 24, 2013 - Views: 5

Rh blood system -

Rh blood system. Difference between ... or damage to motor areas of brain due to deposition of bilirubin in the neuronal cells--- Kernicterus. ... to minimize the ...

Date added: May 19, 2014 - Views: 8

Degradation of heme - KSU

Formation of bilirubin. The first step in the degradation of heme is catalyzed by the microsomalhemeoxygenase system of the reticuloendothelial cells.

Date added: June 28, 2012 - Views: 4

Slide 1

Physical Examination – Assessment of Gestational Age. Two primary evaluation tools used to determine gestational age. Dubowitz Scale. Ballard Scale

Date added: December 27, 2014 - Views: 1

Blood and Blood Component Therapy - Indiana...

Without therapy unconjugated/indirect bilirubin can reach toxic levels ... Kernicterus and Acute Bilirubin Encephalopathy . ... Blood and Blood Component Therapy

Date added: October 24, 2013 - Views: 44

Slide 1

Epidemiology . HCC is the fifth most common cancer and the third most frequent cause of cancer death worldwide, with an estimated 560,000 new cases per year.

Date added: October 18, 2015 - Views: 5

High Risk Neonates - Austin Community College

HIGH RISK NEONATES Presented by Ann ... in hemolysis of fetal RBCs HYPERBILIRUBINEMIA Complications of Hemolytic Disease Kernicterus ... High levels of glucose cross ...

Date added: November 30, 2012 - Views: 96

Kernicterus - NCC Pediatrics Residency

Kernicterus Developmental Pediatrics Louis Meng, PL2 November 12th 2002 History Earliest work on jaundice from Baumes-1785, and Hervieux-1847 Kernicterus was first ...

Date added: October 25, 2011 - Views: 74

Conversion of Amino Acids to Specialized Products

Conversion of Amino Acids to Specialized Products . 1. Overview . In addition to serving as building blocks for proteins, ...

Date added: June 20, 2015 - Views: 3

Penicillins and Cephalosporins - The University of...

(at therapeutically attainable levels) ... Neutropenia Kernicterus in neonates Dicloxicillin Oral NOT equivalent to IV Ox ... Penicillins and Cephalosporins Author:

Date added: October 21, 2011 - Views: 290

Fetal Haemolytic Disease - School of Medicine

Fetal Haemolytic Disease ... Increased bilirubin Jaundice postnatally Kernicterus Prevention Anti-D after any ... Serial measurements of Anti-D levels.

Date added: May 13, 2013 - Views: 6

Hyperbilirubinemia - Oregon Health & Science...

Hyperbilirubinemia Case 1 5 day old ... Serum Bilirubin Level and Kernicterus in 229 Infants ... follow up and check bilirubin levels Risk Factors Without Hemolysis ...

Date added: November 12, 2011 - Views: 64

Cerebral Palsy: The Stigma, The Fears and the...

Cerebral Palsy: The Stigma, The Fears and The ... Kernicterus (excessively high bilirubin ... The GMFCS describes the functional characteristics in five levels, ...

Date added: March 28, 2014 - Views: 6

PowerPoint Presentation

... conditions leading to abnormal levels. ... Complications: anemia; hyperbilirubinemia; kernicterus. Excess unconjugated bilirubin from red cell breakdown.

Date added: March 6, 2012 - Views: 69

Sedatives, Hypnotics & Anxiolytics -

Sedatives, Hypnotics & Anxiolytics. Dr. Sana ... If given repeatedly stores saturate and levels increase leading ... Enzyme induction causes metabolism of bilirubin, ...

Date added: April 27, 2014 - Views: 5

Seminar On Altered kinetics in pediatrics

... ALTERED KINETICS IN PEDIATRICS. ... bilirubin and contribute to high levels of bilirubin in neonate and infants. Displaced bilirubin can cross the blood brain ...

Date added: April 9, 2014 - Views: 5

Common learning issues -

Urine Osmolality. Increased levels: SIADH . ADH is inappropriately secreted despite factors normally would inhibit its secretion. As a result, large quantities of ...

Date added: December 6, 2015 - Views: 2

PowerPoint Presentation

Follow the serum bilirubin level and treat according to the ... End Tidal Carbon Monoxide levels in 20 ... and reduce the risk of BIND and kernicterus ...

Date added: August 23, 2015 - Views: 4

Common learning issues - LSH Student Resources

-Levels can be decreased in patients with ... Compete with bilirubin for binding sites on serum albumin and can cause kernicterus in newborns; can also cause ...

Date added: November 26, 2015 - Views: 1

Neonatal Hyperbilirubinemia - Yale University

Neonatal Hyperbilirubinemia ... conjugating enzymes Pre-term infants can develop encephalopathy or kernicterus at lower total bilirubin levels Indirect ...

Date added: August 8, 2013 - Views: 56

Common neonatal problems - OMC Forum • Index page

Common Neonatal Problems. SafiyaKhamis Al-butaini. ... They are also more likely to develop kernicterus, ... High levels bilirubin may require phototherapy or ...

Date added: August 1, 2013 - Views: 69

Age and Pharmacokinetics Pediatric and Geriatric...

Age and Pharmacokinetics Pediatric and Geriatric Considerations ... Most important in displacement of bilirubin from albumin resulting in toxicity (kernicterus) ...

Date added: October 22, 2011 - Views: 150

Nerve activates contraction - Jefferson County...

Neurolemma. Why is the plasma membrane (neurolemma) of a neuron so important? It is the site of electrical signaling – plays a crucial role in cell to cell ...

Date added: November 24, 2014 - Views: 19

Recommending a Strategy

Chronic Bilirubin Encephalopathy (Kernicterus) ... treatment with phototherapy effectively lowers serum bilirubin levels and diminishes the need for treatment ...

Date added: February 5, 2013 - Views: 27

Neonatal Unconjugated Hyperbilirubinemia

Title: Neonatal Unconjugated Hyperbilirubinemia Author: Pediatrics Last modified by: chiefs Created Date: 10/4/2005 2:02:11 AM Document presentation format

Date added: October 25, 2011 - Views: 170


Identify the issue: societal awareness of kernicterus ... adverse outcome with high bilirubin levels (CDC, AAP, JCAHO ... KERNICTERUS AS A “NEVER EVENT” FOR ...

Date added: November 25, 2011 - Views: 59


2-Give the proper dose for sufficient time to maintain sufficiently high levels of the ... Kernicterus . when given in last 2 ... sulfonamides compete with bilirubin ...

Date added: November 21, 2015 - Views: 1

How to prescribe antibiotics: maybe it’s not as...

Aims & Objectives. To know how to diagnose and manage life-threatening infections. To know how to diagnose and manage common infections . To understand how to ...

Date added: August 2, 2013 - Views: 10

September Board Review - School of Medicine - LSU...

Jaundice/ kernicterus. ... Bilirubin Metabolism. ... Results from high levels of oxygen administration and mechanical ventilation. Question #14.

Date added: December 13, 2015 - Views: 3


Prep trials to prevent transmission with oral agents in women. FEM Prep trial of TDF/FTC: trial discontinued due to lack of efficacy. VOICE study: oral TDF arm halted ...

Date added: October 28, 2014 - Views: 7